The show, formerly produced by TechTV's Annaliza Savage, premiered to viewers of DL.TV on March 15, 2006 and has since received its own website. The show is similar to Dvorak's previous show, Silicon Spin.
The show was streamed live weekly on Wednesdays at 4:00 p.m. ET/1:00 p.m. PT from the Ziff Davis office in San Francisco, California. In addition, it was offered for download in multiple formats on a weekly basis, including as a video or audio podcast on iTunes.
Show guests included Martin Sargent, Neil Gaiman, Adam Curry, Chris DiBona, Om Malik, Larry Lessig, Leo Laporte, Veronica Belmont, John Markoff, Natalie Del Conte, Robert Scoble, Jimmy Wales, Alex Albrecht, Molly Wood and Kevin Rose. Dvorak has humorously mentioned his intention to invite Danica Patrick, the IndyCar driver endorsing Go Daddy, one of the show's sponsors, whose commercial airs in every episode.
In May 2010, the show's "Co-Crank," permanent guest/sidekick Sebastian Rupley, who appeared on the show from its inception, announced he was leaving the show.
On his nightly Tech5 podcast episode for September 15, 2010, host John C. Dvorak announced that they had produced that day's Cranky Geeks show (September 15, 2010) and also the final-ever Cranky Geeks show to be released the following Wednesday, September 22, 2010.